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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa3bc619af5915c1a1a2e983a4976d7fc0328bb41154852b68970b4a2d2f5f52' 
  AND token = 'BTCqO2jn4cSFy4gnP4aU5rEGcGZAJeUrKwIa9aqMW20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}