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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f11ff391f5f4b99f8b0dc3a8819db1c55a2916cc08b1c619cafc4b6e9dd16040' 
  AND token = 'K+7DSkeIIip7zODJZaAAPPzsoW4UrW0IoQ+YyyMWsm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}