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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2945f54f4a364939ca8fd8419642ea599e284422dda6169b53b245d054578518' 
  AND token = 'TR2OVrn9NK2MGRsamI/WRehtRxMLLhTx3VuusGaPXr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}