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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '981f2b18f92a5be62627ae208cbd0b97012047f3286400e0b33eb4c23a102ae3' 
  AND token = 'rqgNs6+8GgTKnOMA9S3aD8ZobPGuHahWkmKZNlnbmts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}