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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a25a3d8155e448f195ff9170be6a18276f8c7cd89017726179ebb1a12898b5a' 
  AND token = '/Hp8IgaYcf8jIcLCd5WGFwAFOwl2nu2g+bLAONx0uTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}