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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ea40cb67702d85bab0ad450c124ce11ccfce4a0501604594a98b57edf6c81e' 
  AND token = '+ePhbMdxEyMs1T5H53yXBpWa/nS8i6mUv0WY7poepIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}