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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc6dee2b0d5290defc80d23a6a0bbcb179acd77f9aa7db477fc38a16f612438' 
  AND token = '+tpFC4/tm3dgiah6YNsr61jZpJONkVjbZfX6+sHfZ5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}