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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '091610e0564e9827fc66fee469a4bf4c07e733ee14b31f0abe36b24aa9f3bcc7' 
  AND token = 'ygeqs9JHdHtiu+t6PbNPcLYrvS1U1EYk4iFTRsbPVeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}