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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b601af90a1f5187eba51a8c8692bd85f0cc6b99f6bab0713acb7c1c3de8d522b' 
  AND token = 'paWv7NXoDrWctVEjLbPC7BuW0iSuL+iua+nkGy7nXz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}