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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a9242b7458e1d774f8fc472e2c2b0f50456080876bf91cb378d80255cea4e4a' 
  AND token = 'ZysCoTz8gE7YmaMkkxYgJ3OUT3uHw8H1OWG3ims/kbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}