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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd653a8202e1eccbc8624b71b4a26f65a40b920b156d41814105cdaacdea62ecb' 
  AND token = '1hfpidZMUiB+d8rsPOty0pwlX8IUEGVNG5eRAcQNnC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}