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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7c1acff22dd79b491c37e42fd470476a263a01f420b6b902f959a0c6ff0a0f' 
  AND token = '+Wygg5kRn0rWuOExBxC+T2OnWf1OozLfyli69AAlzvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}