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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12943de2700142e49caad22e32cb3f91172fbf5499b3826bf3e90f2721e7d85' 
  AND token = '50X/r5TzA594kpaoAXEYQxVdQEajxchKuICFbaTUvGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}