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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c4bf441e69b62b14e43e202ed0591997f7854826e5cb2d4fbf6d2406e17a710' 
  AND token = 'Hs4wfw6WRrUXpJKLHex5ZVrsF9y60M1oRJbaQD3CK3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}