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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b7cd50a8efc7b71b491ed6e6651f4a9de2e6f77c5284c32ae1714a2384993b' 
  AND token = 'OnTTqp+wFX68uAUwnFkQEgw2FezXQzCbyU/sSTJnX78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}