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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2448972c8bdd4444ceae2560074c25e776e494fe39bb4320405fa8d0f77e0d00' 
  AND token = 'RoUtfzjyMY1hiqW4HMsy4tLGXDiH9nZNI0LFu4DaThc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}