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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ffc84aa0c925e5a75eecc8095aefa7169dbcaaae83a503c457e8fee563fd9f5' 
  AND token = 'i4EmhEfYny0j4qhvjVE3K2iSdMUCvNDM+Q1xhfz4l/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}