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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '088f302e460509899617da674635ecf6b2d03746af3b7b67619e1f6eee86c36d' 
  AND token = 'cVV3xP2VBiS1akd0+0BOkpoIVI+Z4zTjalTcI3sKUDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}