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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5ee6ff325a4e70ee8fb56f1db6e81e52ffcd6597388688b151603a2d52f8e7' 
  AND token = 'oBx8a+PdHRXiW6V0IJ/0MoY0lNAriFjYZjEN9UnUKVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}