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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4666eea55fbe0b5aea39dc9bc1f06a127596ece0673ed126f581b91409c74fdb' 
  AND token = 'NSryYnDYrnf7qdvmfeOkg/QsrZR+34nuZNqdxubFOp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}