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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f044dfd4b0a4f30bad854b3d283f8b21b9d900d98adfc644c35a13829da1dc5' 
  AND token = 'OAthlB5yFbuFvu49KhT9uC1Z4c31U3jLMqlGFZo3Me0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}