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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '673d0f6d9c97c1c09ee6062f7327599c823ce50601cd4da05a1f3d4cfd2adf10' 
  AND token = 'fQQwtiW0RJcu5WdsjWsgsfMu8sELCapxIRTeK57yZJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}