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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b8a497680d32a9ee0433f3fc7b334347161c4f90d0f6379d4275413b980757' 
  AND token = '/z4ufdLozRIn8qMU/i5r4xGXsPS9X8wnt1cBImt0Ofk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}