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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ead7a6fd35dcd10a53056a5220e657abafc0b02fe2c57dd9695e82c7c0546e8' 
  AND token = 'MajvjRJAT3iWTOU9xny0NiYhfkUEkQGNH2y4alkyg1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}