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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7201c194ba37184ebe4377f58f50f7ffca01f016b147cf6eb8f86547cb5c4c' 
  AND token = 'QK1LyoKBxp5ALytGK5yT/8vpL6HAPhbrgnQc5sH0Dbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}