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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f11e76bd70b9d7a35c7ffe9302bcd21411632fb2503f04e2405c2625a9abd1c3' 
  AND token = 'MBFrZtOlBT1tSNTIJeN0r5DvFMv316pj8ovDGAhMeMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}