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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ac3f7c8c45ccbd85019ff731244e096a0946e51f4c85b5ce14452d7ea914b1' 
  AND token = 'UWU20dMxlq2aj1XcLWooE/z2pDkhnT3VYDtGZv+Gg4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}