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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b295cb7d86e2f7d2890629ce6e82a0ac94312128d030adb4033ff03f9c103f' 
  AND token = 'N7iULphHR5g3Zy71BygYKdXDU9hTpHSf/+8X7bWF5wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}