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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9129a5ae22c171410b68ab8b29a3cbe3a4eaa4ae208a2efac67d14a67a1a9215' 
  AND token = 'awgG3YreS2Ol6862BrSWppkIqKopz2qp++V3JvlWutk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}