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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0d3c6c815b0659fb4ab4cc88dd54ef72b59679cd93c6a27e4c4a784298c448' 
  AND token = 'TB6JlEUS6UvpLNzFj0sn23lgaczJD+6boRU6rTye8LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}