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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9edcf89cb5109ee45b60b478749e6c6fbcdad40df5f9f86d1e141be1249269a' 
  AND token = 'rAJg8tFd6ine/qxXn4EcgfyzZeqaIvVA+Dzj3wSMa80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}