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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e133bc38d8f33b399bbc82950b8580bff1c44ba067ee5cd592ee1aa0779781' 
  AND token = 'h4zMUQn0FWM1uutZBy4bHrgk9Kmx+4D7HVafFwXbybQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}