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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0d6a9f9967c0604d8e28239514c05a1378da4568650ff3cddd7a98264f0059' 
  AND token = 'uLmysk9eYXhHWol/mnF9qOdJ7h5pdfQ0ZTAD9bo61+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}