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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c484f263d15c8ef3afadc0bcfcda583a188e88d2077914261dea054e321458f' 
  AND token = '3KUqlXLxeW3cICiCVr84GkFkrUnhcIkdKJY5OVd03M4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}