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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c6a011e26d09444e3e06dbc944e91c3c4213890d3a27847a0bfdfb8be8e023' 
  AND token = 'OhwWfkTO5vfc7sN7f0YFKRcNHPmPDG4QsUZ0ubaJKzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}