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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c405b9a63f801fd5d0e24b317be504c33a25634ef73cadddeb76c6b37d605885' 
  AND token = 'HlIxErGO6qX1LIi+VZ4loN+qKePcxDyoOuL11Syv1n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}