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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e29cdec96f8129e3d99974bf385f52de6e3af1a4c374150fc050ef74a335d856' 
  AND token = '/LL2eyHeMn+B6hAYnW9R4nX9M6p0DWQU5r1b/DGb5uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}