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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd020291bb2cb9aca345afda2f2fb30bf022340c6b162021b046e952a3dcffc9' 
  AND token = 'gtAuqS5UzKfwYNCp6hFHJMoVuMrhC/lacFRgQmMg3ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}