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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678c318e75172d474c19c67093d507087c895c8852b491a6ac2ba7279067ac51' 
  AND token = 'XCFkPFrTLv38RLUt7h5KWUb1F1C6QDQoq00bvvTk7Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}