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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f63d67aeb88b995c925e9e5271e3e5ee32f7dff5fff5d3e414e2ac5525ae1306' 
  AND token = 'aNW59lj3AEAcI/UVlUdEKHQc2Nk17ySKdEn+yHELdiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}