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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7870bc70a9a428b610bd0ef27008f7e61bd64bd124741e97043e3e1c1dd6605' 
  AND token = 'oaRc9TLGQAjLbWWkPSV31HmiTQ+1SMlZJ/effzn7i6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}