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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1cf12b56d89477a66587351b733f5ce06ec388c4ec0167cdc3dbe08b4d93512' 
  AND token = 'kHERj1O2YujuzLNPXC1tf/E2R4kJnUm1Ol4BBtxZUQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}