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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd994352b75a3833cd0f30faa31a9d1f085fb325e7815449b8a90699e06676016' 
  AND token = 'rAWTF8SEhR1LHQS8JDrjT5tUA5wU/7qp5UVWDZnYEco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}