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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74447041c577348b46b685a071661a49d0f4187bf1afd9fce1f88f4b93d6b89' 
  AND token = 'JG37orPFmU4lH3jFgvCjd2NLTSdb+PFaaHmj2IFDWMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}