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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfd2abb80c5623a23a96681994383c8fb47c691d60effcc90b35abd42abb5060' 
  AND token = '+p+sc7LlOB5iJlF5xLAdvTIdt02JZ2tIOoj9pLDLbSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}