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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f121052f57c17bf217b27ca78218b9768317674c9cee6d999b2c465d892d987' 
  AND token = 'RAVisE1YwjwZ1ApPOe2ImGUq1Oo54z9vGrJAcPTzyfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}