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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780e42832c84473bd4ac1c7ad1ff1729da7a1b789aefe76d1aa0e52cbaca3921' 
  AND token = '92cStCV4W1abQOSmIsdtm6wKYFHRge7NMIakVFBuC6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}