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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ea6de021593c1143e7780a87cdd47c4d178bb5f4a39297a11ad9f0a4689df6' 
  AND token = 'XBpJ8wywE535AhK0wGyrtmj69Xw2hAC4xR5lvGMhNBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}