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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d77ac887801434263ad295d4b776b70605855a5ae5f241de5a0c60c9ec5bb61' 
  AND token = 'WzAfpzmdgzYRLLheHODYapLTEI9GZT49COm3R9d8SlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}