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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '706a6a57760a5f413f5e17061635eca6621fa7e764b0ecbd3b2a0364395ab7c2' 
  AND token = 'xH5ZDzunjDtXa5O1X18Ufu++q0bDhQCwjiJUT1lCJ50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}